Heparin Heuristics

JHL Consultants

Medical Applications

Downloads

Updated 9th June 2024

NOTICE:

● Version 6 has a slightly modified way of estimating statistics and now uses the trimmed median of all slopes for a particular oral anticoagulant for estimating the heparin dose suggested to achieve the desired ACT. The application has now been validated and two publications are available:

1. Cumpston P, Phillips KP. A Novel Method for Calculating Heparin Dosing to Rapidly Achieve Target Anticoagulation for Cardiac Procedures. Journal of Atrial Fibrillation. 2024;18.

2. Cumpston PH, Duffy R. Effective Heparin Administration and Reversal in Cardiac Surgery: A Pilot Study. Cardiology Research. 2024;6(1):1–10.

● Version 5.1 corrects a significant bug that occurs when the record is saved before all the data fields needed to calculate the individual patient's heparin:ACT dose-response curve have been entered. The decision has also been taken to provide a version that includes information for both catheter ablation cases and cardiac surgical cases, reducing the number of versions to two, one for Windows and one for OSX (MacIntosh) computers.

● Version 5.0 provides an encrypted database for confidentiality. De-identified data can still be exported for review and research purposes.

The latest version works for both Catheter Ablation cases and Cardiac Surgery. The use of an infusion is not required, but may be helpful in maintaining the desired activated clotting time (ACT). The ACT after re-infusion of pump blood can be used to estimate any additional doses of protamine that may be required.

OSX 64 Bit Version 6.0 (MacIntosh)

Windows 64 Bit Version 5.2 (Microsoft)